PT  - JOURNAL ARTICLE
ED  - Vidt, Donald G.
ED  - Bakst, Alan
AU  - Prichard, B.N.C.
TI  - Alpha- and beta-blocking agents: pharmacology and properties
DP  - 1991 Jul 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 337--350
VI  - 58
IP  - 4
4099  - http://www.ccjm.org/content/58/4/337.short
4100  - http://www.ccjm.org/content/58/4/337.full
SO  - Cleve Clin J Med1991 Jul 01; 58
AB  - Adrenergic receptors have been separated into alpha and beta groups, which have then been further subdivided. Agents have been developed that block each type of receptor with varying degrees of specificity between the sub-types, leading to differences in pharmacodynamic profile. A more recent innovation has been the development of multiple action beta-blocking drugs, ie, those not only blocking the beta receptors but also posessing a peripheral vasodilator effect that may be due to alpha blockade, beta-2 stimulation, or a vasodilator action independent of either alpha or beta receptors.