PT - JOURNAL ARTICLE AU - Mgbojikwe, Nkemdilim AU - Jones, Steven R. AU - Leucker, Thorsten M. AU - Brotman, Daniel J. TI - Infective endocarditis: Beyond the usual tests AID - 10.3949/ccjm.86a.18120 DP - 2019 Aug 01 TA - Cleveland Clinic Journal of Medicine PG - 559--567 VI - 86 IP - 8 4099 - http://www.ccjm.org/content/86/8/559.short 4100 - http://www.ccjm.org/content/86/8/559.full SO - Cleve Clin J Med2019 Aug 01; 86 AB - Infective endocarditis remains a diagnostic challenge. Although echocardiography is still the mainstay imaging test, it misses up to 30% of cases. Newer imaging tests—4-dimensional computed tomography (4D CT), fluorodeoxy glucose positron emission tomography (FDG-PET), and leukocyte scintigraphy—are increasingly used as alternative or adjunct tests for select patients. They improve the sensitivity of clinical diagnosis of infective endocarditis when appropriately used, especially in the setting of a prosthetic valve.