%0 Journal Article %A James W. Smith %A Paul S. Malchesky %A Yukihiko Nose %T Membrane plasmapheresis and the developing technology of plasma therapy %D 1984 %J Cleveland Clinic Journal of Medicine %P 135-142 %V 51 %N 1 %X Therapeutic plasmapheresis has been used increasingly in the treatment of a variety of diseases. Membrank plasma filters have been developed that produce a cell-free and particulate-free plasma ideally suited for on-line plasma treatment systems. Clinical experience with sorbent and filtration techniques for solute removal indicate promising directions for plasma therapy and its role in treating and understanding disease. %U https://www.ccjm.org/content/ccjom/51/1/135.full.pdf