RT Journal Article SR Electronic T1 Membrane plasmapheresis and the developing technology of plasma therapy JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 135 OP 142 VO 51 IS 1 A1 James W. Smith A1 Paul S. Malchesky A1 Yukihiko Nose YR 1984 UL http://www.ccjm.org/content/51/1/135.abstract AB Therapeutic plasmapheresis has been used increasingly in the treatment of a variety of diseases. Membrank plasma filters have been developed that produce a cell-free and particulate-free plasma ideally suited for on-line plasma treatment systems. Clinical experience with sorbent and filtration techniques for solute removal indicate promising directions for plasma therapy and its role in treating and understanding disease.