RT Journal Article SR Electronic T1 Preclinical evaluation of a biolized temporary ventricular assist device JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 119 OP 126 VO 51 IS 1 A1 Yozu, Ryohei A1 Golding, Leonard A. R. A1 Jacobs, Gordon A1 Murabayashi, Shun A1 Harasaki, Hiroaki A1 Kiraly, Raymond J. A1 Nosé, Yukihiko YR 1984 UL http://www.ccjm.org/content/51/1/119.abstract AB An external clinical temporary ventricular assist device (VAD) has been developed with the use of our universal, multipurpose cardiac prosthesis with specially designed inflow and outflow cannulas. The cannulas allow flexibility in application of the VAD, which can access the vascular system via either the atrium or ventricle for inflow, and the aorta or pulmonary artery for outflow. A high-pressure pneumatic actuator activates the pusher-plate of the VAD. The clinical drive system for this VAD has complete redundancy and automatic switching to a backup system in the event of any component failure. Six VADs were tested in calves as a temporary left VAD before clinical use and functioned well.