TY - JOUR T1 - Macromolecular solute kinetics in on-line membrane plasma treatment systems JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 127 LP - 133 VL - 51 IS - 1 AU - Paul S. Malchesky AU - Jeffery J. Starre AU - Jan Wojcicki AU - Andrzej Werynski AU - James W. Smith AU - Yasuhisa Abe AU - Yukihiko Nose Y1 - 1984/03/20 UR - http://www.ccjm.org/content/51/1/127.abstract N2 - Macromolecule removal by membrane plasma separation with on-line plasma filtration in rheumatoid arthritis patients undergoing cryofiltration treatments has been quantified. A single pool model provided good estimates of post-treatment concentrations of immunoglobulins, albumin, total globulin, and total cholesterol. Net generation of these solutes as well as rheumatoid factor and circulating immune complexes has been shown to be highly individual and related to intertreatment durations and concomitant drug therapy. ER -