PT  - JOURNAL ARTICLE
AU  - Dyment, Paul G.
AU  - Norris, Donald G.
TI  - Prognosis for adolescents with Hodgkin’s disease
DP  - 1983 Sep 21
TA  - Cleveland Clinic Journal of Medicine
PG  - 291--294
VI  - 50
IP  - 3
4099  - http://www.ccjm.org/content/50/3/291.short
4100  - http://www.ccjm.org/content/50/3/291.full
SO  - Cleve Clin J Med1983 Sep 21; 50
AB  - From 1972 to 1983, 68 adolescents, aged 12 to 20 years (median 17.6 years), with Hodgkin’s disease received treatment at the Cleveland Clinic. Although the overall male:female ratio was 1.2:1.0, male predominance was greater in younger adolescents. The histopathologic distribution was overwhelmingly nodular sclerosing (69%), but 24% were mixed cellularity, and 7% were lymphocyte- predominant. There was no statistical relationship between histopathology and survival. All patients were pathologically staged (PS): PS-I = 11 patients, PS-II = 26 patients, PS-III = 17 patients, and PS-IV = 14 patients. The overall five-year survival rate was 83%, and there was no significant difference between pathological stage and chance of survival. Treatment programs had been based on pathological staging, usually irradiation therapy for stages I and II, combination chemotherapy for stage IV, and both modalities combined for stage III. This therapy has resulted in an excellent five-year survival rate for these adolescents.