RT Journal Article
SR Electronic
T1 Combined desmopressin (DDAVP) and chlorpropamide therapy for diabetes insipidus with absent thirst
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 351
OP 352
VO 50
IS 3
A1 Redmond, Geoffrey P.
A1 Rothner, A. David
A1 Hahn, Joseph F.
A1 Schumacher, O. Peter
YR 1983
UL http://www.ccjm.org/content/50/3/351.abstract
AB A patient with neurogenic diabetes insipidus and defective thirst regulation due to a craniopharyngioma is described who responded to a combination of desmopressin (DDAVP) and chlorpropamide with improved thirst regulation and decreased urine output. When DDAVP was discontinued he became hypernatremic. This patient required both DDAVP and chlorpropamide to maintain normonatremia.