TY - JOUR T1 - Current management of Barrett esophagus and esophageal adenocarcinoma JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 724 LP - 732 DO - 10.3949/ccjm.86a.18106 VL - 86 IS - 11 AU - Tavankit Singh AU - Vedha Sanghi AU - Prashanthi N. Thota Y1 - 2019/11/01 UR - http://www.ccjm.org/content/86/11/724.abstract N2 - Barrett esophagus is found in 5% to 15% of patients with gastroesophageal reflux disease and is a precursor of esophageal adenocarcinoma, yet the condition often goes undiagnosed. Patients with reflux disease who are male, over age 50, or white, and who smoke or have central obesity or a family history of Barrett esophagus or esophageal adenocarcinoma, should undergo initial screening endoscopy and, if no dysplasia is noted, surveillance endoscopy every 3 to 5 years. Dysplasia is treated with endoscopic eradication by ablation, resection, or both. Chemoprotective agents are being studied to prevent progression to dysplasia in Barrett esophagus. The authors discuss current recommendations for screening and management. ER -