RT Journal Article
SR Electronic
T1 Role of the matrix in modifying the growth of prostatic epithelial cells in vitro
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 411
OP 418
VO 51
IS 2
A1 Mark J. Noble
A1 Saing H. Lee
A1 Winston K. Mebust
YR 1984
UL http://www.ccjm.org/content/51/2/411.abstract
AB Preliminary data demonstrate that migration, proliferation, and differentiation of prostatic epithelial cells in vitro is altered when the cells are grown on an extracellular matrix rather than on bare plastic. Clonal plating efficiencies are used to distinguish this growth and to identify ways to provide an in vitro model for further study of prostatic carcinogenesis. Consequently, this method, with suggested refinements, may improve the understanding of prostate cancer and related disorders.