RT Journal Article SR Electronic T1 An overview of therapeutic drug monitoring principles JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 241 OP 254 VO 51 IS 2 A1 Charles E. Pippenger A1 Ronald P. Lesser YR 1984 UL http://www.ccjm.org/content/51/2/241.abstract AB Recent technological advances allow determination of anticonvulsant blood levels. Consequently, the principles of pharmacokinetics can be applied in managing patients with seizures. We review these principles as well as those of therapeutic drug monitoring for the control of antiepileptic drug levels.