PT  - JOURNAL ARTICLE
AU  - Katzin, William E.
AU  - Barna, Barbara P.
AU  - Clough, John D.
AU  - Clements, Mary A.
TI  - Neutrophil Dysfunction
DP  - 1986 Sep 21
TA  - Cleveland Clinic Journal of Medicine
PG  - 299--306
VI  - 53
IP  - 3
4099  - http://www.ccjm.org/content/53/3/299.short
4100  - http://www.ccjm.org/content/53/3/299.full
SO  - Cleve Clin J Med1986 Sep 21; 53
AB  - The polymorphonuclear leukocyte (PMN), or neutrophil, plays a central role in the defense of the body against acute bacterial infection. PMNsalso migrate to sites of tissue necrosis and actively participate in the early stages of repair. They may have tumoricidal activity and thereby play a role in the immune surveillance which is thought to be important in controlling neoplastic disease. Two cases which illustrate defects in neutrophil motility and oxidative metabolism are described. A number of intrinsic neutrophil defects are reviewed.