PT - JOURNAL ARTICLE AU - Wong, James AU - Reddy, S. Sethu K. AU - Klein, Allan L. TI - Anorectic drugs and valvular heart disease: A biological and clinical perspective DP - 1998 Jan 01 TA - Cleveland Clinic Journal of Medicine PG - 35--41 VI - 65 IP - 1 4099 - http://www.ccjm.org/content/65/1/35.short 4100 - http://www.ccjm.org/content/65/1/35.full SO - Cleve Clin J Med1998 Jan 01; 65 AB - The epidemiologic and pathologic evidence that fenfluramine and related drugs cause valvular heart disease is still speculative. However, at present, there is no alternative explanation for the cases of valvular disease found in patients taking these drugs, and there is evidence that similar substances can cause similar lesions. The manufacturer of fenfluramine and dexfenfluramine has prudently removed them from sale pending further studies.