RT Journal Article
SR Electronic
T1 Anorectic drugs and valvular heart disease: A biological and clinical perspective
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 35
OP 41
VO 65
IS 1
A1 Wong, James
A1 Reddy, S. Sethu K.
A1 Klein, Allan L.
YR 1998
UL http://www.ccjm.org/content/65/1/35.abstract
AB The epidemiologic and pathologic evidence that fenfluramine and related drugs cause valvular heart disease is still speculative. However, at present, there is no alternative explanation for the cases of valvular disease found in patients taking these drugs, and there is evidence that similar substances can cause similar lesions. The manufacturer of fenfluramine and dexfenfluramine has prudently removed them from sale pending further studies.