RT Journal Article SR Electronic T1 Angioplasty or fibrinolysis for acute MI? JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 75 OP 81 VO 65 IS 2 A1 Brener, Sorin J. YR 1998 UL http://www.ccjm.org/content/65/2/75.abstract AB The angioplasty substudy of the GUSTO lib trial confirmed that the short-term results of primary angioplasty are better than those of fibrinolytic therapy in patients with acute myocardial infarction (Ml). In the largest and most rigorous study of this topic performed to date, 9.6% of patients who underwent primary angioplasty either died or suffered a disabling stroke or another myocardial infarction within 30 days, compared with 13.7% of patients who received fibrinolytic therapy, for an odds ratio of 0.67 (P = .033). This difference was less than in previous studies, possibly in part because fibrinolytic therapy has improved. The findings underscore the importance of promptly restoring complete, brisk, antegrade flow in the infarct-related artery, regardless of what treatment is used.