PT - JOURNAL ARTICLE ED - Hoffman, Gary S. AU - Langford, Carol A. TI - The diagnostic utility of c-ANCA in Wegener’s granulomatosis DP - 1998 Mar 01 TA - Cleveland Clinic Journal of Medicine PG - 135--140 VI - 65 IP - 3 4099 - http://www.ccjm.org/content/65/3/135.short 4100 - http://www.ccjm.org/content/65/3/135.full SO - Cleve Clin J Med1998 Mar 01; 65 AB - Anti-neutrophil cytoplasmic antibodies with a cytoplasmic staining pattern (c-ANCA) have been found to have a high degree of sensitivity and specificity for Wegener’s granulomatosis. Nevertheless, despite the attraction of using this autoantibody as a diagnostic test, in almost all instances it should not be used in place of a biopsy to diagnose Wegener’s granulomatosis.