PT  - JOURNAL ARTICLE
AU  - Donald R. Steinmuller
TI  - Cyclosporine nephrotoxicity
DP  - 1989 Jan 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 89--95
VI  - 56
IP  - 1
4099  - http://www.ccjm.org/content/56/1/89.short
4100  - http://www.ccjm.org/content/56/1/89.full
SO  - Cleve Clin J Med1989 Jan 01; 56
AB  - Cyclosporine is a potent and useful immunosuppressive agent used primarily in Conjunction with solid organ transplantation. The most serious adverse reaction that limits its use is nephrotoxicity due to effects on the renal vasculature, glomeruli, and tubular function. These effects result in a variety of clinical syndromes. This review outlines the clinical syndromes and discusses ways to minimize nephrotoxicity in patients receiving cyclosporine.