TY - JOUR T1 - Cyclosporine nephrotoxicity JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 89 LP - 95 VL - 56 IS - 1 AU - Donald R. Steinmuller Y1 - 1989/01/01 UR - http://www.ccjm.org/content/56/1/89.abstract N2 - Cyclosporine is a potent and useful immunosuppressive agent used primarily in Conjunction with solid organ transplantation. The most serious adverse reaction that limits its use is nephrotoxicity due to effects on the renal vasculature, glomeruli, and tubular function. These effects result in a variety of clinical syndromes. This review outlines the clinical syndromes and discusses ways to minimize nephrotoxicity in patients receiving cyclosporine. ER -