PT - JOURNAL ARTICLE ED - Hart, William R. AU - Sharad D. Deodhar TI - C-reactive protein: the best laboratory indicator available for monitoring disease activity DP - 1989 Mar 01 TA - Cleveland Clinic Journal of Medicine PG - 126--130 VI - 56 IP - 2 4099 - http://www.ccjm.org/content/56/2/126.short 4100 - http://www.ccjm.org/content/56/2/126.full SO - Cleve Clin J Med1989 Mar 01; 56 AB - Recent technical advances in measurement of serum C-reactive protein (CRP) have made this laboratory test highly specific, sensitive, reproducible, quantitative, and easy and rapid to perform. Several studies have shown that serial and quantitative measurement of serum C R P can be very helpful in monitoring disease activity in a wide variety of clinical situations, and that C R P testing offers distinct advantages over testing for any of the other acute-phase reactants. C R P testing is superior to erythrocyte sedimentation rate (ESR) measurements on clinical, scientific, and practical grounds, and it is strongly recommended that serious consideration be given to replacing ESR with C R P testing for monitoring disease activity.