PT - JOURNAL ARTICLE AU - Meeker, David P. TI - Pulmonary infiltrates and eosinophilia revisited DP - 1989 Mar 01 TA - Cleveland Clinic Journal of Medicine PG - 199--211 VI - 56 IP - 2 4099 - http://www.ccjm.org/content/56/2/199.short 4100 - http://www.ccjm.org/content/56/2/199.full SO - Cleve Clin J Med1989 Mar 01; 56 AB - Diseases characterized by pulmonary infiltrates and peripheral eosinophilia have been grouped based on a common clinical presentation. Early classification schemes viewed these syndromes as a continuum with significant overlap between categories. Although understanding of certain of these syndromes has increased, this classification system remains a useful framework for identification and diagnosis. A t present, we cannot predict which patients with isolated lung involvement will progress to involvement of other organs. Early diagnosis and close follow-up are critical. Corticosteroids are the primary treatment in most of these diseases; cytotoxic agents also have a role. The role of the eosinophil in the disease process and the syndromes included in the differential diagnosis are reviewed. Loeffler’s syndrome, eosinophilic pneumonia, the hypereosinophilic syndrome, allergic bronchopulmonary aspergillosis, Churg-Strauss syndrome, and tropical pulmonary eosinophilia are discussed in detail.