PT  - JOURNAL ARTICLE
AU  - Huerter, Christopher J.
AU  - Bergfeld, Wilma F.
AU  - Wagner, William O.
AU  - Dijkstra, Jacob W. E.
TI  - Treatment of chronic idiopathic urticaria with astemizole
DP  - 1989 May 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 263--266
VI  - 56
IP  - 3
4099  - http://www.ccjm.org/content/56/3/263.short
4100  - http://www.ccjm.org/content/56/3/263.full
SO  - Cleve Clin J Med1989 May 01; 56
AB  - Astemizole is anew, long-acting H1 receptor antagonist that has proven effective in controlling the signs and symptoms of chronic idiopathic urticaria, without the sedative and anticholinergic side effects that typify use of many antihistamines. In an eight-week open study of 20 patients, astemizole significantly decreased the signs and symptoms of urticaria, as well as the severity of urticaria by anatomic location. Five patients reported complete clearing. Modest weight gain while on chronic therapy appears to be a significant side effect.