PT  - JOURNAL ARTICLE
AU  - Krall, Patricia L.
AU  - Mazanec, Daniel J.
AU  - Wilke, William S.
TI  - Methotrexate for corticosteroid-resistant polymyalgia rheumatica and giant cell arteritis
DP  - 1989 May 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 253--257
VI  - 56
IP  - 3
4099  - http://www.ccjm.org/content/56/3/253.short
4100  - http://www.ccjm.org/content/56/3/253.full
SO  - Cleve Clin J Med1989 May 01; 56
AB  - Three patients (one with polymyalgia rheumatica with jaw claudication and two with biopsy-proven giant cell arteritis) were initially treated using prednisone (4 0 - 6 0 mg daily). T h e response was good in all three, but each experienced exacerbation of symptoms and elevation of Westergren sedimentation rates (W S R) with dose reduction. The addition of methotrexate (7.5-12.5 mg/wk) resulted in diminished symptoms and lower W S R and proved to be steroid-sparing.