RT Journal Article
SR Electronic
T1 Drug-induced osteoporosis
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 297
OP 303
VO 56
IS 3
A1 Mazanec, Daniel J.
A1 Grisanti, Joseph M.
YR 1989
UL http://www.ccjm.org/content/56/3/297.abstract
AB Use of corticosteroids has been most frequently associated with bone loss, but heparin and methotrexate, when used in relatively high doses, have also been linked to the development of osteoporosis. Clinical features of bone loss associated with these agents, possible pathophysiologic mechanisms, and strategies for avoiding this complication are reviewed.