RT Journal Article
SR Electronic
T1 New options for diagnosing and treating acromegaly
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 343
OP 349
VO 65
IS 7
A2 Wilke, William S.
A1 Barkan, Ariel L.
YR 1998
UL http://www.ccjm.org/content/65/7/343.abstract
AB Insulin-like growth factor 1 (IGF-1) is the final pathway of the growth hormone cascade, and is a better clinical measure of acromegaly than growth hormone itself. In patients with acromegaly, medical treatment w i t h a somatostatin analog normalizes growth hormone and IGF-1 levels and produces clinical improvement quickly.