PT  - JOURNAL ARTICLE
ED  - Vidt, Donald G.
AU  - Mary Beth Bobek
AU  - Alejandro C. Arroliga
TI  - Stress ulcer prophylaxis: The case for a selective approach
DP  - 1997 Nov 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 533--542
VI  - 64
IP  - 10
4099  - http://www.ccjm.org/content/64/10/533.short
4100  - http://www.ccjm.org/content/64/10/533.full
SO  - Cleve Clin J Med1997 Nov 01; 64
AB  - Although stress-related mucosal damage is common (and potentially serious) in critically ill patients, the risk of clinically significant gastrointestinal bleeding appears to be confined to patients with certain factors: mechanical ventilation, coagulopathy, multiple trauma, increased intracranial pressure, and multi-organ dysfunction. Because prophylactic therapy also poses risks, we advocate reserving it for patients in these high-risk groups.