RT Journal Article
SR Electronic
T1 Stress ulcer prophylaxis: The case for a selective approach
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 533
OP 542
VO 64
IS 10
A2 Vidt, Donald G.
A1 Bobek, Mary Beth
A1 Arroliga, Alejandro C.
YR 1997
UL http://www.ccjm.org/content/64/10/533.abstract
AB Although stress-related mucosal damage is common (and potentially serious) in critically ill patients, the risk of clinically significant gastrointestinal bleeding appears to be confined to patients with certain factors: mechanical ventilation, coagulopathy, multiple trauma, increased intracranial pressure, and multi-organ dysfunction. Because prophylactic therapy also poses risks, we advocate reserving it for patients in these high-risk groups.