TY - JOUR T1 - Stress ulcer prophylaxis: The case for a selective approach JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 533 LP - 542 VL - 64 IS - 10 AU - Mary Beth Bobek AU - Alejandro C. Arroliga A2 - Vidt, Donald G. Y1 - 1997/11/01 UR - http://www.ccjm.org/content/64/10/533.abstract N2 - Although stress-related mucosal damage is common (and potentially serious) in critically ill patients, the risk of clinically significant gastrointestinal bleeding appears to be confined to patients with certain factors: mechanical ventilation, coagulopathy, multiple trauma, increased intracranial pressure, and multi-organ dysfunction. Because prophylactic therapy also poses risks, we advocate reserving it for patients in these high-risk groups. ER -