PT  - JOURNAL ARTICLE
AU  - Cumming, David C.
TI  - Use of spironolactone in treatment of hirsutism
DP  - 1990 May 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 285--287
VI  - 57
IP  - 3
4099  - http://www.ccjm.org/content/57/3/285.short
4100  - http://www.ccjm.org/content/57/3/285.full
SO  - Cleve Clin J Med1990 May 01; 57
AB  - Spironolactone (Aldactone), 100 mg to 200 mg daily, has antiandrogenic effects that may enhance treatment of androgen-excess syndromes, particularly severe hirsutism. Combination therapy with an oral contraceptive or with dexamethasone appears to have a beneficial effect. Side effects are transient. The drug should be avoided during pregnancy and in women who have a family history of breast cancer, although there is no proven association between spironolactone and breast malignancy.