RT Journal Article
SR Electronic
T1 Use of spironolactone in treatment of hirsutism
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 285
OP 287
VO 57
IS 3
A1 Cumming, David C.
YR 1990
UL http://www.ccjm.org/content/57/3/285.abstract
AB Spironolactone (Aldactone), 100 mg to 200 mg daily, has antiandrogenic effects that may enhance treatment of androgen-excess syndromes, particularly severe hirsutism. Combination therapy with an oral contraceptive or with dexamethasone appears to have a beneficial effect. Side effects are transient. The drug should be avoided during pregnancy and in women who have a family history of breast cancer, although there is no proven association between spironolactone and breast malignancy.