PT  - JOURNAL ARTICLE
AU  - Grum, Daniel F.
AU  - Rice, Thomas W.
TI  - Methemoglobinemia from topical benzocaine
DP  - 1990 Jun 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 357--359
VI  - 57
IP  - 4
4099  - http://www.ccjm.org/content/57/4/357.short
4100  - http://www.ccjm.org/content/57/4/357.full
SO  - Cleve Clin J Med1990 Jun 01; 57
AB  - Acute cyanosis and methemoglobinemia developed following topical application and partial ingestion of benzocaine for esophagogastroduodenoscopy. A diagnosis of acute toxic methemoglobinemia should be considered when cyanosis, with or without neurologic symptoms, occurs following the use of local anesthetics in the absence of cardiopulmonary disease. Laboratory tests should include oxygen saturation and methemoglobin concentration. Management includes supplemental oxygen administration and intravenous methylene blue.