RT Journal Article
SR Electronic
T1 Methemoglobinemia from topical benzocaine
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 357
OP 359
VO 57
IS 4
A1 Grum, Daniel F.
A1 Rice, Thomas W.
YR 1990
UL http://www.ccjm.org/content/57/4/357.abstract
AB Acute cyanosis and methemoglobinemia developed following topical application and partial ingestion of benzocaine for esophagogastroduodenoscopy. A diagnosis of acute toxic methemoglobinemia should be considered when cyanosis, with or without neurologic symptoms, occurs following the use of local anesthetics in the absence of cardiopulmonary disease. Laboratory tests should include oxygen saturation and methemoglobin concentration. Management includes supplemental oxygen administration and intravenous methylene blue.