PT - JOURNAL ARTICLE AU - Holden, David A. AU - Mehta, Atul C. TI - Evaluation of wheezing in the nonasthmatic patient DP - 1990 Jun 01 TA - Cleveland Clinic Journal of Medicine PG - 345--352 VI - 57 IP - 4 4099 - http://www.ccjm.org/content/57/4/345.short 4100 - http://www.ccjm.org/content/57/4/345.full SO - Cleve Clin J Med1990 Jun 01; 57 AB - Wheezing is a nonspecific manifestation of airway obstruction. Even though bronchial asthma is the most common cause of wheezing, a variety of pulmonary and nonpulmonary conditions can present with this symptom. In recent years methacholine provocation challenge has simplified detection of bronchial asthma; however, establishing accurate diagnosis of other causes of wheezing is important because each condition requires specific treatment. This article describes a methodical approach to the diagnosis of wheezing in patients who are not asthmatic.