RT Journal Article SR Electronic T1 Evaluation of wheezing in the nonasthmatic patient JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 345 OP 352 VO 57 IS 4 A1 Holden, David A. A1 Mehta, Atul C. YR 1990 UL http://www.ccjm.org/content/57/4/345.abstract AB Wheezing is a nonspecific manifestation of airway obstruction. Even though bronchial asthma is the most common cause of wheezing, a variety of pulmonary and nonpulmonary conditions can present with this symptom. In recent years methacholine provocation challenge has simplified detection of bronchial asthma; however, establishing accurate diagnosis of other causes of wheezing is important because each condition requires specific treatment. This article describes a methodical approach to the diagnosis of wheezing in patients who are not asthmatic.