PT - JOURNAL ARTICLE AU - Edward M. Cordasco, Jr AU - S. Beder AU - Adele Coltro AU - S. Bavbek AU - H. Gurses AU - Atul C. Mehta TI - Clinical features of the yellow nail syndrome DP - 1990 Jul 01 TA - Cleveland Clinic Journal of Medicine PG - 472--476 VI - 57 IP - 5 4099 - http://www.ccjm.org/content/57/5/472.short 4100 - http://www.ccjm.org/content/57/5/472.full SO - Cleve Clin J Med1990 Jul 01; 57 AB - The yellow nail syndrome is a rare cause of exudative pleural effusions. Diagnosis is based on the presence of typical clinical features, striking nail changes, lymphedema, and pleural effusions of undetermined etiology. There is no direct relationship between the syndrome and primary immunologic disorders, malignancies, endocrine abnormalities, or connective tissue diseases. In patients with symptomatic pleural effusions, pleurodesis is beneficial but no treatment for the nail changes has been devised.