RT Journal Article SR Electronic T1 Pancreas transplantation: state of the art JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 564 OP 570 VO 57 IS 6 A2 Hoogwerf, Byron J. A1 Grundfest-Broniatowski, Sharon YR 1990 UL http://www.ccjm.org/content/57/6/564.abstract AB Improvements in technique and in the diagnosis of rejection have led to progressively better pancreas transplant graft and patient survival rates over the past 5 years. Refinements in organ preservation are making it easier for centers to share organs, with better immunologic matching and therefore additional improvement in results. As new immunosuppressive agents become available, pancreas transplantation may be an option for diabetic patients early in the course of their disease, before secondary complications become disabling.