RT Journal Article SR Electronic T1 Parenteral nitrogen mustard for inflammatory arthritis JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 643 OP 646 VO 57 IS 7 A1 William S. Wilke A1 Charles Sexton A1 Willard Steck YR 1990 UL http://www.ccjm.org/content/57/7/643.abstract AB A patient with progressive psoriatic arthritis refractory to methotrexate therapy was treated empirically with intravenous nitrogen mustard, or HN2. His response to therapy was compared with the responses of five rheumatoid arthritis patients treated with the same regimen. A t 14 days after therapy was begun the patient with psoriatic arthritis showed significant improvement, at least comparable to that observed in the rheumatoid arthritis group. Intravenous HN2 therapy may be an alternative to methotrexate for progressive psoriatic arthritis.