RT Journal Article SR Electronic T1 Serial electrophysiologic testing of drug therapy in supraventricular tachycardia related to accessory pathways JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 622 OP 626 VO 57 IS 7 A1 Hassan M.K. Nagi A1 Sergio L. Pinski A1 Sherif Mokhtar A1 Yehia Saad A1 James D. Maloney YR 1990 UL http://www.ccjm.org/content/57/7/622.abstract AB Data are limited on the use of serial electrophysiologic testing of drug therapy in patients with supraventricular tachycardia associated with accessory pathways, including the Wolff-Parkinson-White syndrome. Twenty-four highly symptomatic patients (aged 36 ± 11 years) with SVT related to accessory pathways underwent electrophysiologic studies to select an effective chronic oral treatment. Conventional (verapamil, propranolol, quinidine, disopyramide) and investigational (amiodarone, aprindine, propafenone) drugs were used alone and in combination if necessary. It was determined that serial electrophysiologic studies could identify potentially effective treatments in 6 6 % of patients with reentrant S V T involving accessory pathways, and the findings were highly predictive of long-term clinical outcome.