PT  - JOURNAL ARTICLE
AU  - Azmy R. Boutros
AU  - Emmanuel L. Bravo
AU  - Giorgio Zanettin
AU  - Ralph A. Straffon
TI  - Perioperative management of 63 patients with pheochromocytoma
DP  - 1990 Oct 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 613--617
VI  - 57
IP  - 7
4099  - http://www.ccjm.org/content/57/7/613.short
4100  - http://www.ccjm.org/content/57/7/613.full
SO  - Cleve Clin J Med1990 Oct 01; 57
AB  - During a 10-year period, 60 patients with confirmed diagnoses of pheochromocytoma underwent a total of 63 surgical procedures. To control extreme blood pressure elevations, 6 patients received phenoxybenzamine preoperatively and 28 patients received prazosin. The remaining 29 patients received neither drug. Intravenous sodium nitroprusside and nitroglycerin, alone or in combination, were used in all but 10 patients to control intraoperative hypertensive episodes. One patient died after surgery due to pre-existing intracranial malignant tumor. All other patients were discharged from the hospital with no clinical evidence of stroke or myocardial infarction. We conclude that pheochromocytoma patients can undergo successful surgery without preoperative profound and long-lasting alpha adrenergic blockade.