PT - JOURNAL ARTICLE AU - Edward M. Cordasco, Jr AU - Muzaffar Ahmad AU - Atul Mehta AU - Felipe Rubio TI - The effects of steroid therapy on pulmonary hypertension secondary to fibrosing mediastinitis DP - 1990 Oct 01 TA - Cleveland Clinic Journal of Medicine PG - 647--652 VI - 57 IP - 7 4099 - http://www.ccjm.org/content/57/7/647.short 4100 - http://www.ccjm.org/content/57/7/647.full SO - Cleve Clin J Med1990 Oct 01; 57 AB - Mediastinal fibrosis, a rare cause of pulmonary hypertension, may produce cough, dyspnea, and hemoptysis. Steroid therapy has been suggested for individuals with progressive symptoms, but data demonstrating the efficacy of such therapy are lacking. We present a case of pulmonary hypertension secondary to fibrosing mediastinitis. Hemodynamic and scintigraphic studies performed before and after a trial of corticosteroid therapy were unable to demonstrate any therapeutic benefit from the corticosteroids. In order to achieve better use of steroids for the treatment of this disease, we suggest that similar determinations be made on other patients with mediastinal fibrosis who receive such treatment.