RT Journal Article SR Electronic T1 The effects of steroid therapy on pulmonary hypertension secondary to fibrosing mediastinitis JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 647 OP 652 VO 57 IS 7 A1 Edward M. Cordasco, Jr A1 Muzaffar Ahmad A1 Atul Mehta A1 Felipe Rubio YR 1990 UL http://www.ccjm.org/content/57/7/647.abstract AB Mediastinal fibrosis, a rare cause of pulmonary hypertension, may produce cough, dyspnea, and hemoptysis. Steroid therapy has been suggested for individuals with progressive symptoms, but data demonstrating the efficacy of such therapy are lacking. We present a case of pulmonary hypertension secondary to fibrosing mediastinitis. Hemodynamic and scintigraphic studies performed before and after a trial of corticosteroid therapy were unable to demonstrate any therapeutic benefit from the corticosteroids. In order to achieve better use of steroids for the treatment of this disease, we suggest that similar determinations be made on other patients with mediastinal fibrosis who receive such treatment.