PT  - JOURNAL ARTICLE
AU  - Robert Detrano
AU  - Conrad Simpfendorfer
AU  - John Yiannikas
AU  - Donald A. Underwood
AU  - Ernest E. Salcedo
AU  - Michael Rollins
TI  - Comparative accuracy of wall-motion analysis by digital subtraction and first-pass radionuclide ventriculography
DP  - 1985 Jun 20
TA  - Cleveland Clinic Journal of Medicine
PG  - 239--245
VI  - 52
IP  - 2
4099  - http://www.ccjm.org/content/52/2/239.short
4100  - http://www.ccjm.org/content/52/2/239.full
SO  - Cleve Clin J Med1985 Jun 20; 52
AB  - Forty-six patients referred for coronary angiography and direct contrast ventriculography were also examined using first-pass radionuclide and digital subtraction ventriculography for detection of wall motion abnormalities at rest. All three ventriculograms were reviewed by independent observers and the five wall segments graded on the right anterior oblique view as normal, mildly hypokinetic, moderately hypokinetic, severely hypokinetic, akinetic, or dyskinetic. Though the resting radionuclide ventriculogram was superior for identifying ventricles which were normal according to direct contrast ventriculography (89% versus 63%), digital subtraction ventriculography was more sensitive for identification of abnormal ventricles (100% versus 74%), particularly in identifying akinetic segments (77% versus 23%) and distinguishing segmental from diffuse ventricular dysfunction (100% versus 44%). Digital ventriculography caused overestimation of wall segment abnormality, while radionuclide ventriculography caused underestimation of segmental dysfunction. The authors conclude that digital subtraction ventriculography is more sensitive than radionuclide ventriculography but also less specific.