PT  - JOURNAL ARTICLE
AU  - Khaled Alshabani
AU  - Thomas R. Gildea
AU  - Michael Machuzak
AU  - Joseph Cicenia
AU  - Umur Hatipoğlu
TI  - Bronchoscopic lung volume reduction with valves: What should the internist know?
AID  - 10.3949/ccjm.87a.19083
DP  - 2020 May 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 278--287
VI  - 87
IP  - 5
4099  - http://www.ccjm.org/content/87/5/278.short
4100  - http://www.ccjm.org/content/87/5/278.full
SO  - Cleve Clin J Med2020 May 01; 87
AB  - Traditional therapies for emphysema such as bronchodilators and anti-inflammatory drugs have limited value due to permanent structural changes in the emphysematous lung that result in hyperinflation. Surgical lung volume reduction partially corrects hyperinflation by removing emphysematous lung and is an option in selected patients, but it carries a risk of morbidity and death. Valve therapy is a less-invasive option that involves bronchoscopic implantation of 1-way valves in emphysematous lung segments to allow air flow and mucus clearance in the direction of central airways. The authors review the rationale, evidence, and applications of valve therapy.