RT Journal Article
SR Electronic
T1 Bronchoscopic lung volume reduction with valves: What should the internist know?
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 278
OP 287
DO 10.3949/ccjm.87a.19083
VO 87
IS 5
A1 Khaled Alshabani
A1 Thomas R. Gildea
A1 Michael Machuzak
A1 Joseph Cicenia
A1 Umur Hatipoğlu
YR 2020
UL http://www.ccjm.org/content/87/5/278.abstract
AB Traditional therapies for emphysema such as bronchodilators and anti-inflammatory drugs have limited value due to permanent structural changes in the emphysematous lung that result in hyperinflation. Surgical lung volume reduction partially corrects hyperinflation by removing emphysematous lung and is an option in selected patients, but it carries a risk of morbidity and death. Valve therapy is a less-invasive option that involves bronchoscopic implantation of 1-way valves in emphysematous lung segments to allow air flow and mucus clearance in the direction of central airways. The authors review the rationale, evidence, and applications of valve therapy.