PT - JOURNAL ARTICLE AU - James T. McMahon TI - Analytical electron microscopy in pneumoconiosis DP - 1985 Dec 21 TA - Cleveland Clinic Journal of Medicine PG - 503--512 VI - 52 IP - 4 4099 - http://www.ccjm.org/content/52/4/503.short 4100 - http://www.ccjm.org/content/52/4/503.full SO - Cleve Clin J Med1985 Dec 21; 52 AB - The study of pneumoconiosis has been greatly facilitated by use of the analytical electron microscope. Morphologic, crystallographic, and chemical analyses may be obtained on submicroscopic particles using various analytical modalities. Since there is no destruction of tissue, as in other analytical techniques, analytical electron microscopy can help relate the effects of foreign particles to localized cell and tissue reactions. An overview of the different modalities of the analytical electron microscope is presented, along with cases illustrative of their use.