RT Journal Article
SR Electronic
T1 Monoclonal gammopathy of undetermined significance: A primary care guide
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 39
OP 46
DO 10.3949/ccjm.86a.17133
VO 86
IS 1
A1 Khouri, Jack
A1 Samaras, Christy
A1 Valent, Jason
A1 Garcia, Alex Mejia
A1 Faiman, Beth
A1 Mathur, Saveta
A1 Hamilton, Kim
A1 Nakashima, Megan
A1 Kalaycio, Matt
YR 2019
UL http://www.ccjm.org/content/86/1/39.abstract
AB Monoclonal gammopathy of undetermined significance (MGUS) is commonly diagnosed in outpatients being worked up for an array of clinical concerns. It carries a risk of progression to myeloma and other lymphoproliferative disorders that, albeit low (1% per year), warrants regular follow-up. Patients with MGUS can be risk-stratified on the basis of the amount and type of their monoclonal protein as well as whether they have an abnormal light-chain ratio. Here, we provide a guide to the diagnosis, workup, and management of MGUS.