PT - JOURNAL ARTICLE AU - Sidra Azim AU - Christian Nasr TI - Subclinical hypothyroidism: When to treat AID - 10.3949/ccjm.86a.17053 DP - 2019 Feb 01 TA - Cleveland Clinic Journal of Medicine PG - 101--110 VI - 86 IP - 2 4099 - http://www.ccjm.org/content/86/2/101.short 4100 - http://www.ccjm.org/content/86/2/101.full SO - Cleve Clin J Med2019 Feb 01; 86 AB - Subclinical hypothyroidism is defined by an elevated serum thyroid-stimulating hormone (TSH) level along with a normal free thyroxine (T4) level. Whether it should be treated remains controversial. Currently, the best practical approach is to base treatment decisions on the degree of TSH elevation, thyroid autoimmunity, and associated comorbidities.