RT Journal Article SR Electronic T1 Subclinical hypothyroidism: When to treat JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 101 OP 110 DO 10.3949/ccjm.86a.17053 VO 86 IS 2 A1 Sidra Azim A1 Christian Nasr YR 2019 UL http://www.ccjm.org/content/86/2/101.abstract AB Subclinical hypothyroidism is defined by an elevated serum thyroid-stimulating hormone (TSH) level along with a normal free thyroxine (T4) level. Whether it should be treated remains controversial. Currently, the best practical approach is to base treatment decisions on the degree of TSH elevation, thyroid autoimmunity, and associated comorbidities.