TY - JOUR T1 - Giant cell arteritis: An updated review of an old disease JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 465 LP - 472 DO - 10.3949/ccjm.86a.18103 VL - 86 IS - 7 AU - Timothy Rinden AU - Eric Miller AU - Rawad Nasr Y1 - 2019/07/01 UR - http://www.ccjm.org/content/86/7/465.abstract N2 - Giant cell arteritis is a common systemic vasculitis that affects the elderly and has a variable clinical presentation. Physicians should be aware of its different clinical phenotypes so that they can recognize it early and promptly initiate glucocorticoids, the mainstay of therapy. Clinicians should also be familiar with the toxicity of glucocorticoids and how to manage adverse effects. Tocilizumab, an interleukin 6 receptor inhibitor, is emerging as a glucocorticoid-sparing treatment, though its long-term safety and efficacy are still under study. ER -