RT Journal Article
SR Electronic
T1 Giant cell arteritis: An updated review of an old disease
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 465
OP 472
DO 10.3949/ccjm.86a.18103
VO 86
IS 7
A1 Timothy Rinden
A1 Eric Miller
A1 Rawad Nasr
YR 2019
UL http://www.ccjm.org/content/86/7/465.abstract
AB Giant cell arteritis is a common systemic vasculitis that affects the elderly and has a variable clinical presentation. Physicians should be aware of its different clinical phenotypes so that they can recognize it early and promptly initiate glucocorticoids, the mainstay of therapy. Clinicians should also be familiar with the toxicity of glucocorticoids and how to manage adverse effects. Tocilizumab, an interleukin 6 receptor inhibitor, is emerging as a glucocorticoid-sparing treatment, though its long-term safety and efficacy are still under study.