A high-PEEP, low Fio2 strategy
| Fio2 | PEEP |
|---|---|
| 0.3 | 5 |
| 0.3 | 8 |
| 0.3 | 10 |
| 0.3 | 12 |
| 0.3 | 14 |
| 0.4 | 16 |
| 0.4 | 16 |
| 0.5 | 18 |
| 0.5 | 18 |
| 0.5-0.8 | 20 |
| 0.8 | 22 |
| 0.9 | 22 |
| 1.0 | 22 |
| 1.0 | 24 |
Use a minimum positive end-expiratory pressure (PEEP) of 5 cm H2O. Consider using incremental combinations of fraction of inspired oxygen Fio2 and PEEP as shown to achieve PaO2 of 5–80 mm Hg or SpO2 88%–95%.
From the Acute Respiratory Distress Syndrome Network, reference 6.